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Subtracting this 0.5 g of reabsorbed B12 from the 1.5 g that normalizes blood parameters results in a requirement of 1.0 g absorbed per day (for those without pernicious anemia)

On the other hand, genetic deletion of PNPLA2 has been shown to improve metabolic disease as well

You should take B12 shots if you suffer from B12 deficiency, especially if you are not able to absorb B12 through the stomach (pernicious anemia)

If your doctor has prescribed B12 injections for weight loss, our treatment center can help

When it comes to supplements, taking high doses of vitamin C at the same time as your B12 shot might slightly lower the amount of B12 your body can use, but this is more relevant for oral B12 supplements than injections